Novel Methods in Single Arm Trials

What you will learn

Single arm trials are common when diseases are rare, or when randomization is unethical or impossible. In the absence of a control arm, there has been increased use of external control arms as acceptable evidence by regulatory bodies including the Food and Drug Agency (FDA), European Medicines Agency (EMA) and Health Canada. From this report you will learn:

What are single arm trials, and when are they used
Gold standard analytic approaches for single arm trials
How targeted maximum likelihood estimation provide new insights

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Novel Methods in Single Arm Trials

What you will learn

Read the full report

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